The molecular diagnostics (i.e. chromosomal or genetic markers) associated with the brain Tumour during a Cancer Care Spell, taken from the World Health Organisation classification.
National Codes:
| 1 | Evidence of IDH1 or IDH2 mutation (Retired 01 April 2017) |
| 2 | Evidence of methylation of the MGMT gene CpG island (Retired 01 April 2017) |
| 3 | Evidence of total loss of 1p and 19q (Retired 01 April 2017) |
| 4 | Evidence of KIAA 1549-BRAF fusion gene (Retired 01 April 2017) |
| 5 | Other (Retired 01 April 2017) |
| 06 | Evidence of ALK rearrangement |
| 07 | Evidence of native ALK |
| 08 | Evidence of ATRX mutation |
| 09 | Evidence of wt ATRX |
| 10 | Evidence of BRAF V600E mutation |
| 11 | Evidence of wt BRAF |
| 12 | Evidence of KIAA1549-BRAF fusion |
| 13 | Evidence of BRAF/RAF1 mutations, or fusions involving genes other than KIAA1549 |
| 14 | Evidence of C11orf95-RELA fusion |
| 15 | Evidence of native C11orf95 and RELA |
| 16 | Evidence of amplification or fusion of C19MC locus (chr.19q13.42) |
| 17 | Evidence of unaltered C19MC locus (chr.19q13.42) |
| 18 | Evidence of CDK4/6 amplification |
| 19 | Evidence of CDK4/6 normal copy number |
| 20 | Evidence of CDKN2A locus homozygous deletion |
| 21 | Evidence of CDKN2A locus normal copy number |
| 22 | Evidence of CCND1/2/3 amplification |
| 23 | Evidence of CCND1/2/3 normal copy number |
| 24 | Evidence of CTNNB1 mutation |
| 25 | Evidence of wt CTNNB1 |
| 26 | Evidence of amplification of EGFR |
| 27 | Evidence of mutation / rearrangement of EGFR |
| 28 | Evidence of unaltered EGFR |
| 29 | Evidence of EWSR1-FLI1 fusion |
| 30 | Evidence of native EWSR1 and FLI1 |
| 31 | Evidence of FGFR1 mutation / rearrangement / fusio |
| 32 | Evidence of unaltered FGFR1 |
| 33 | Evidence of H3F3A/H3F3B (H3.3) K27M mutation |
| 34 | Evidence of H3F3A/H3F3B (H3.3) wt K27 |
| 35 | Evidence of H3F3A/H3F3B (H3.3) G34R/V mutation |
| 36 | Evidence of H3F3A/H3F3B (H3.3) wt G34 |
| 37 | Evidence of HIST1H3B K27M mutation |
| 38 | Evidence of HIST1H3B wt K27 |
| 39 | Evidence of HIST1H3C K27M mutation |
| 40 | Evidence of HIST1H3C wt K27 |
| 41 | Evidence of ID2 amplification |
| 42 | Evidence of ID2 normal copy number |
| 43 | IDH1 (codon 132) or IDH2 (codon 172) mutation identified |
| 44 | IDH1 (codon 132) and IDH2 (codon 172) wt confirmed |
| 45 | Evidence of KLF4 K409Q and TRAF7 mutations |
| 46 | Evidence of wt KLF4 and TRAF7 |
| 47 | Evidence of MAP2K1 mutation |
| 48 | Evidence of wt MAP2K1 |
| 49 | Evidence of MET amplification |
| 50 | Evidence of MET normal copy number |
| 51 | Evidence of significant MGMT promoter methylation |
| 52 | Evidence of unmethylated MGMT promoter |
| 53 | Evidence of MYC/MYCN amplification |
| 54 | Evidence of MYC/MYCN normal copy number |
| 55 | Evidence of NF1 biallelic loss / mutation |
| 56 | Evidence of unaltered NF1 |
| 57 | Evidence of NF2 biallelic loss / mutation |
| 58 | Evidence of unaltered NF2 |
| 59 | Evidence of NKTR fusions |
| 60 | Evidence of native NKTR |
| 61 | Evidence of PTEN biallelic loss / mutation |
| 62 | Evidence of unaltered PTEN |
| 63 | Evidence of SDHB or SDHD mutation |
| 64 | Evidence of wt SDHB and SDHD |
| 65 | Evidence of SHH pathway activation |
| 66 | Evidence of normal SHH pathway |
| 67 | Evidence of inactivation of SMARCB1 (INI1 |
| 68 | Evidence of wt SMARCB1 (INI1) |
| 69 | Evidence of inactivation of SMARCA4 |
| 70 | Evidence of wt SMARCA4 |
| 71 | Evidence of TERT promotor mutation 7299 |
| 72 | Evidence of wt TERT promotor |
| 73 | Evidence of TP53 mutation |
| 74 | Evidence of wt TP53 |
| 75 | Evidence of TSC1 or TSC2 mutation |
| 76 | Evidence of wt TSC1 and TSC2 |
| 77 | Evidence of VHL mutation |
| 78 | Evidence of wt VHL gene |
| 79 | Evidence of WNT pathway activation |
| 80 | Evidence of normal WNT pathway |
| 81 | Evidence of WWTR1-CAMTA1 fusion |
| 82 | Evidence of native WWTR1 and CAMTA1 |
| 83 | Evidence of codeletion of chr.1p and chr.19q |
| 84 | Evidence of total chr.1p loss but normal copy number of chr.19q |
| 85 | Evidence of normal copy number of both chr.1p and chr.19q |
| 86 | Evidence of monosomy chr.6 |
| 87 | Evidence of chr.6 normal copy number |
| 88 | Evidence of polysomy chr.7 |
| 89 | Evidence of chr.7 normal copy number |
| 90 | Evidence of loss of chr.10 or chr.10q |
| 91 | Evidence of chr.10 normal copy number |
| 92 | Evidence of loss of chr.22 or chr.22q |
| 93 | Evidence of chr.22 or chr.22q normal copy number |
| 98 | Other (not listed) |
This attribute is also known by these names:
| Context | Alias |
|---|---|
| plural | MOLECULAR DIAGNOSTIC CODES |