INTERNATIONAL CLASSIFICATION FOR INTRAOCULAR RETINOBLASTOMA

A

Small Tumours away from the foveola and disc:

• Tumours

  less than 3mm in greatest dimension confined to the retina and

• Located at least 3mm from the foveola and 1.5mm from the optic disc

B

All remaining Tumours confined to the retina:

• All Tumours confined to the retina not in group A

• Subretinal fluid (without subretinal seeding) less than 3mm from the base of the Tumour

C

Local subretinal fluid or seeding:

• Subretinal fluid alone greater than 3mm to less than 6mm from the Tumour

• Vitreous seeding or subretinal seeding less than 3mm from Tumour

D

Diffuse subretinal fluid or seeding:

• Subretinal fluid alone greater than 6mm from the Tumour

• Vitreous seeding or subretinal seeding greater than 3 mm from Tumour

E

Presence of one or more of these poor prognosis features:

• Greater than 2/3 globe filled with Tumour

• Tumour

  in anterior segment

• Tumour

  in or on the ciliary body

• Iris neovascularisation

• Neovascular glaucoma

• Opaque media from haemorrhage

• Tumour

  necrosis with septic orbital cellulitis

• Pthisis bulbi